Not all cartoon complexions were created equal. Snow White got lucky with her peaches-and-cream skin (and a couple ampules of Botox?). But sun spots, wrinkles and warts still plague the evil villains and grinches of our youth, so we got top derms to diagnose and treat them. 

SpongeBob's childhood acne destroyed the collagen in his skin, leaving behind indentations and collagen loss. “SpongeBob is suffering from adolescent acne. Now, he no longer wants his face to look like a sponge (he will keep his name but get rid of his sponge-y face),” says Dr. Brandt.

At-Home Treatment: “Acne scars at home respond somewhat to a prescription retinoid and by using mild exfoliator, such as my microdermabrasion. He should still use his sponge-y face to absorb sunscreen every day because sun exposure can make acne scars worse.”

In-Office Treatment: “To make his face look clear and not “sponge-y,” he should come into the office for a Fraxel laser treatment series of less invasive, non-ablative erbium fraxel lasers 3-4, or a stronger carbon dioxide Fraxel laser.”

The Grinch’s angry ways have left him with mean 11s, aka glabella lines, between his eyes and brows. "The lines around our eyes and in between our brows, or 11s, that the Grinch seems to have are generally the result of wear and tear to the areas of our face that are involved in its movement," says Dr. Gross. "After years of squinting or scowling, the collagen and elastin eventually break down, resulting in creases."

At-Home Treatment: Believe it or not, retraining ourselves not to make some very basic facial expressions, such as scowling, can make all the difference in minimizing the appearance of lines. This would definitely help the Grinch and the town of Who-ville. I would also give the Grinch the Ferulic Acid + Retinol Brightening Solution so he can begin preventative aging measures at-home.

In-Office Treatment: If the Grinch were to come in-office for those “11s”, I would recommend that he come into my office for a Botox consultation. Botox can be used to treat deeply entrenched expression lines that have been there for quite some time – though an injectable filler may also be required for optimum results.

Luban is one ugly character. He could use some serious help in the skincare department. "Luban is really aged and has lost a lot of volume," says Dr. Karcher.

At-Home Treatment: "He can use ANEW Clinical Pro Line Eraser with A-F33 for wrinkles and ANEW Clinical Absolute Even for dark spots.

In-Office Treatment: "I'd put back volume into his face with Sculptra. He should also use hyaluronic fillers for lines and Botox for crows feet. A peel would also help with his dark spots."

Family Guy's Herbert may have been a little too careless in the sun when he was younger. Now, he's paying for it with sun spots, otherwise known as solar lentigines. "It appears Herbert has spent a little too much time with the fam at the beach, and his sunscreen has been out of reach," says Dr. Brandt. "Now we gotta get his face looking smooth."

At Home Treatment: "Herbert has got to start cracking down and wearing a sunscreen with SPF of at least 30 with UVA/UVB protection if he wants to get anywhere with his sunspots. At home, Herbert should start using a retinoid (like my glow overnight resurfacing serum) paired with a bleaching agent with a lightening ingredient, such as hydroquinone, at night.

In-Office Treatment: Herbert’s spots will fade but if they do not totally clear up, get him into the office and we can zap his sunspots off using a q-switch ruby alexandrite laser or ND-yag laser.

The Witch from Hansel and Gretel spent too much time kidnapping children when she should have been treating her skin.

At-Home Treatment: Although many of the witch's skin problems should be treated at the derm's office, a moisturizing wrinkle reducer like this Avon Anew Clinical Advanced Wrinkle Corrector wouldn't hurt.

In-Office Treatment: "She needs a nose job, face job, eye lift," says Dr. Karcher. "Sculptra would be helpful, as well as cryotherapy for the warts or skin lumps. Botox and a filler would help with her wrinkling."

Family Guy's Chris has a pimple so big, it warrants its own name and zip code. "However tempting it may be to pop a blemish, I urge my patients to try their hardest to resist and Chris would be no exception," says Dr. Gross. "If a blemish is red and elevated, this indicates that there is some degree of inflammation and infection. It is imperative to reduce the elevated bump and draw out the infection without picking at the blemish, which may lead to scarring."

At-Home Treatment: "For a spot treatment, look for sulfur as the main ingredient.  Sulfur controls the oil that feeds bacteria, thus reducing spots altogether. It also calms through osmosis to relieve swelling and draws out the infection to flatten the blemish. The blemish must be flat before it can be eradicated." Try Dr. Gross' Correct & Perfect Spot Treatment at home. "Chris should also prevent future acne flare-ups by applying a thin layer of either benzoyl peroxide or salicylic acid solution all over face," says Dr. Gross.

In-Office Treatment: "An in-office option is to come in for a cortisone shot. This is recommended to reduce swelling and expedite the healing process of the blemish."

Futurama's Professor Farnsworth might have been getting a little too comfortable around the sun lately. "Sunspots, like those seen on Professor Farnsworth’s head, are actually our skin’s defensive reaction to the sun," says Dr. Gross. "They form as a result of excess pigmentation due to too much ultraviolet light."

At-Home Treatment: "Vitamin C is also a powerful antioxidant and when applied topically in a product such as the Hydra-Pure Vitamin C Brightening Serum, it can be extremely effective in fading those unsightly spots. It’s also essential for Professor Farnsworth to apply a sunscreen of SPF 15 or higher EVERY DAY, especially since he is constantly flying by the sun."

In-Office Treatment: "Though at-home options can be effective, there is only one way to completely remove Professor Farnsworth’s sunspots, which is by laser. The Q-Switch YAG Laser is designed specifically for the purpose of removing these spots. It selectively attacks darker colored spots on the surface of the skin, while the healthy normal skin is left unaffected. The cost of a session can range $500 and up depending on the individual and the number of spots that must be treated."

Shaggy and his pal Scooby-Doo are always so scared, it looks like they're losing sleep over it. Perhaps they're party animals! "It seems as if Shaggy is partying a little too much at night and not getting enough sleep," says Dr. Brandt.

At-Home Treatment: "He should watch his salt intake and sleep with his head elevated. This will take away any fluid accumulation under his eye. Use an eye cream at home with caffeine (like my r3p eye) to reduce puffiness."

In-Office Treatment: "If this does not make a significant indent into his puffs, he may have to get his shag cut. Also, we could remove his under eye fat with lower lid blepharoplasty."